The Endocannabinoid System
The Endocannabinoid System. Have you heard of it? In 1988 we discovered our first cannabinoid receptor in a rat’s brain. Then in 1993 another type of cannabinoid receptor was found as part of the immune and nervous system. Thus making the 1992 discovery of anandamide the endocannabinoid, a naturally occurring endogenous cannabinoid, all the more interesting.
But what is a cannabinoid?
Cannabinoid (noun): Any of a group of closely related compounds that include cannabinol and the active constituents of cannabis.
Wikipedia says, “A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain. Ligands for these receptor proteins include the endocannabinoids (produced naturally in the body by animals), the phytocannabinoids (found in cannabis and some other plants), and synthetic cannabinoids (manufactured artificially). The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis. Cannabidiol (CBD) is another major constituent of the plant. There are at least 113 different cannabinoids isolated from cannabis, exhibiting varied effects.”
Well isn’t that interesting, cannabis is full of cannabinoids, our bodies naturally produce endocannabinoids. No wonder so many people have found relief or improved their health with cannabis, the compounds found in the the plant are synergistic with our own bodies! Let’s talk about what cannabinoids do.
What is a cannabinoids job?
To interact with cells in your body to produce health benefits. After the receptor is engaged, multiple pathways are activated. It was thought that cannabinoid receptors mainly inhibited the adenylate cyclase, and positively influenced inwardly rectifying some channels. However, a much more complex picture has appeared in different cell types, implicating many more other channels.
As a frame of reference we are learning the following benefits:
Alzheimer’s Disease, Cancer, Crohn’s Disease, Multiple Sclerosis, Neuropathic pain, Parkinson’s Disease, PTSD
Anxiety, Cancer, Chronic Pain, Depression, Diabetes, Epilepsy, Psychotic Disorders
Anti-Depressant, Anti-Fungal, Anti-Inflammatory, Anti-Tumor, Encourages Brain Growth
Anti-Asthmatic, Antibiotic, Appetite Stimulant, Pain reliever, Potential Medication for ALS Patients, Potential Medication for Glaucoma, Sedative
Antibiotic, Antidepressant & Mood-Stabilizer, Anti-Tumor, Pain Reliever, Possible Treatment for Psoriasis
Anticonvulsant, Neuroprotective, Promotes Weight Loss
Anti-Nausea, Appetite Stimulator
THCa and CBDa
Anti-inflammatory, Antioxidant, Improved intestinal function, Improved neural function
Intriguing information right? I mean look at all of those conditions! How many of you or people you know suffer from a variety of the listed ailments? Some people are using very expensive and harmful pharmaceutical drugs to aid in the battle against many of those symptoms. Many will suffer from side effects from those pharmaceutical drugs while trying to treat themselves, ironically creating a whole new problem or host of problems. If only they had a naturally occurring system in their bodies that could aid them in relief with a simple plant-based compatible medicine!!! Oh wait, they do. (This is also why full lab testing profiles are so important ladies, know what cannabinoids and terpenoids at what concentrations are in your medicine!)
It is time to embrace the reality of Cannabis. It is no longer the boogieman but a saving grace. Cannabis is providing children suffering from seizures and cancers with a better quality of life, enabling our seniors to battle parkinson’s, alzheimer’s and dementia, assisting the mentally ill with an alternative and partner in achieving quality mental health. Let us not overlook the importance of easing anxiety and depression that is so widespread among women. How many of us are cannabinoid deficient? Well, that’s a whole new blog post in itself ladies.
So that is our summary The Endocannabinoid System, and with that we wrap our Summer of Truth campaign. We hope you enjoyed the last 3 months worth of content and you learned something new! Be sure to buy YOUR Summer of Truth merchandise for August with “The Endocannabinoid System” messaging, remember 50% of proceeds go directly to the ASPCA!!! Last day to purchase is TUESDAY, August 22ND!!!
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